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  • Volume 5
  •  Issue 7
    • Publication Date: December 2007


Sarcomatoid Collecting-Duct Carcinoma of the Kidney


Slim Charfi, Lobna Ayadi, Sameh Ellouze, Abdelmajid Khabir, Imen Chtourou, Naourez Gouiaa, Ibticem Bahri, Tahya Sellami-Boudawara

Collecting duct carcinoma is a distinct entity among renal cell carcinoma, which is characterized by an aggressive behavior. Sarcomatoid variants of this tumor are rarely described. We report the case of a 62-year-old woman who presented with a left kidney tumor. A radical nephrectomy was performed. The tumor was firm with a white appearance, located in the medulla with infiltrating margins. Pathological examination showed a biphasic tumor with carcinomatous areas consisting of a collecting-duct carcinoma and sarcomatous areas with malignant fibrous histiocytoma-like appearance. Immunohistochemical studies confirmed the diagnosis of sarcomatoid collecting-duct carcinoma. The patient died 8 months after the diagnosis.

Key words: CD15, Keratin, Tubulopapillary growth pattern, Vimentin


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