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  • Volume 5
  •  Issue 5
    • Publication Date: June 2007


Successful Treatment of Metastatic Androgen-Independent Prostate Carcinoma in a Transsexual Patient


Tanya B. Dorff, Ronald L. Shazer, Edward M. Nepomuceno, Steven J. Tucker

The occurrence of prostate carcinoma in transsexual patients has rarely been reported. These cases present a unique challenge in that such patients are effectively receiving androgen deprivation therapy. By definition, their disease is androgen-independent prostate cancer, and the role of local therapy is undefined. We report on a male-to-female transsexual patient with metastatic prostate cancer treated successfully with combination chemotherapy after previous standard therapy failed.

Key words: Adrenolytic therapy, Chemotherapy, Radiation therapy, Second-line therapy


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