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  • Volume 5
  •  Issue 5
  • Publication Date: June 2007


Synchronous Sertoli Cell and Serous Cystadenoma Tumors of the Ovaries with Mixed Epithelial and Stromal Tumor of the Kidney: A Case Report


Cléber Sérgio da Silva, Sheila Jorge Adad, Joao Carlos Saldanha, Cristiane Gobbo Cançado, Carlos Bachi, Eddie Fernando Candido Murta

We present a rare case of a 68-year-old postmenopausal woman with a mobile, hard, and painless pelvic abdominal mass that was palpated to the umbilical scar. Ultrasonography demonstrated a solid mass in the upper pole of the right kidney and a predominantly solid pelvic abdominal mass. Serum testosterone was 413 ng/dL. The patient underwent laparotomy on the renal tumor, which was thought to have a probable ovarian metastasis. Bilateral ovariectomy and right nephrectomy were performed. Immunohistochemical and histopathologic assessment identified a right ovarian Sertoli cell tumor, a left ovarian serous cystadenoma, and a mixed epithelial-stromal tumor in the kidney with positive hormonal receptor. Because our patient had an ovarian neoplasm producing steroids and a kidney tumor expressing hormonal receptors, the hypothesis of possible endocrine dependence in the pathogenesis of mixed epithelial stromal tumor is reinforced.

Key words: Hormone receptor, Immunohistochemistry, Inhibin, Sex-cord stromal tumors



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